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What are antimetabolites?

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A compound that closely resembles a metabolite in molecular structure but is metabolically inactive is called an antimetabolite; such a substance is often used as a drug in the treatment of malignant disease. When introduced into the body, it is mistaken by the cell for the metabolite it simulates, thus preventing the cell from using the genuine substance necessary to its life and growth. It is difficult to design molecules so that they will be metabolic poisons for malignant cells and not for normal cells as well.

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