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In biology the modern revolution began in the 19th cent. with the publication of Charles Darwin's theory of evolution (1859) and Gregor Mendel's theory of genetics, which was largely ignored until the end of the century. With the work of Hugo de Vries around the turn of the century biological evolution came to be interpreted in terms of mutations that result in a genetically distinct species; the survival of a given species was thus related to its ability to adapt to its environment through such mutations.
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