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In the lungs, each iron atom combines reversibly with a molecule of oxygen. Each hemoglobin molecule also has attached a single cysteine amino acid, which attracts nitric oxide from the lungs. The enriched hemoglobin circulates and is carried through the body to the tissues, where the nitric oxide dilates the small capillaries, allowing hemoglobin to deliver its oxygen to the tissues. Then the oxygen- and nitric oxide-free hemoglobin molecule picks up carbon dioxide and free nitric oxide and transports both back to the lungs, where they are exhaled as waste.
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