How does trypsin compare to chymotrypsin?

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Trypsin, produced in an inactive form by the pancreas, is remarkably similar in chemical composition and in structure to the other chief pancreatic proteinase, chymotrypsin. Both enzymes also appear to have similar mechanisms of action; residues of histidine and serine are found in the active sites of both. The chief difference between the two molecules seems to be in their specificity, that is, each is active only against the peptide bonds in protein molecules that have carboxyl groups donated by certain amino acids.

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Similar questions: How are trypsin and chymotrypsin different? How are trypsin and chymotrypsin similar? What is the difference between trypsin and chymotrypsin? [ Hide these questions ]

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