Are hallucinogenic drugs man-made or natural in their origin?

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Mescaline, or peyote , which comes from the cactus Lophophora williamsii ; psilocin and psilocybin, from the mushrooms Psilocybe mexicana and Stropharia cubensis ; and LSD , synthesized from lysergic acid, found in the fungus Claviceps purpurea (see ergot ). These alkaloids have also been produced synthetically. Newer hallucinogens, such as PCP (phencyclidine, or "angel dust" ), a drug originally used as an anesthetic, and MDMA ( "Ecstasy" ), an amphetamine derivative, were common in the 1980s. Marijuana has hallucinogenic properties but is pharmacologically distinct.

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