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What is needed for blood clotting?

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Prothrombin, a substance essential to the clotting mechanism, is produced by the liver in the presence of vitamin K. When the body is deficient in this vitamin, bleeding is more difficult to control. In hemophiliacs, or "bleeders," the blood's coagulation time is greatly prolonged (see hemophilia ).

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Get more facts and information about blood clotting . Or, view the full encyclopedia entry from The Columbia Encyclopedia, Sixth Edition.

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