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Astor's most ambitious venture, establishment of a post at Astoria , Oreg., to control the Columbia River valley fur trade, was made under a subsidiary, the Pacific Fur Company. His early operations around the Great Lakes were under another subsidiary, the South West Company, in which Canadian merchants had a part. The War of 1812 destroyed both companies. In 1817, after an act of Congress excluded foreign traders from U.S. territory, the American Fur Company commanded the trade in the Lakes region. An alliance made in 1821 with the Chouteau interests of St. Louis gave the company a monopoly of the trade in the Missouri River region and later in the Rocky Mts.
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