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What are possible causes of leukemia?

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Possible causes include exposure to certain chemicals (e.g., benzene), chromosomal abnormalities such as Down syndrome , exposure to ionizing radiation, certain drugs (e.g., alkylating agents used in cancer treatment), and infection with retroviruses such as HTLV-I, a relative of the AIDS virus. All of these agents are suspected of causing mutations or other disruptions that interfere with the normal regulation of cell growth and division in leukocytes.

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