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In 256 BC, Diodotus I was made satrap, and a little later he assumed complete independence. His successor, Euthydemus, successfully resisted attempts (208-206 BC) to bring Bactria back into the empire. Euthydemus' son Demetrius made Bactria a powerful state. The Seleucid ruler, Antiochus IV, sent Eucratidas into Bactria, and Eucratidas in 167 BC brought about the death of Demetrius but was himself slain in 159 BC Menander, Demetrius' general, continued to exercise power until his death in 145 BC Bactria later (c.130 BC) became part of the Kushan empire. It was subjugated by the Ephthalites in the 5th cent. and partially by the Turks in the 6th cent.
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