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People with Down syndrome have an increased incidence of infection, childhood leukemia, congenital heart defects, and respiratory problems, but modern medical treatment has improved the life expectancy from 9 (in 1910) to 55 (in 1995). Mental retardation varies widely, from minimal to severe. The great majority of those who have the disorder attend public schools and as adults can live independently or in group homes. After age 35 individuals with the syndrome develop the neurological changes of Alzheimer's disease , and many develop the dementia that accompanies them.
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