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The Monophysites remained aloof, and the West was virtually alienated. Justinian's successors alternately favored and suppressed Monophysitism, but by 600 the lines of schism had hardened; the Coptic Church (see under Copts ), the Jacobite Church of Syria, and the Armenian Church , all Monophysite, were established. Monotheletism was a 7th-century attempt to reconcile orthodoxy with Monophysitism.
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