Why aren't nucleic acid synthesis inhibitors widely used for clinical purposes?

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Most substances that inhibit nucleic acid synthesis, such as nitrogen mustard , cyclophosphamide ( Cytoxan ), chloramphenicol , actinomycin , and colchicine , are not widely used clinically because they are too toxic.

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Similar questions: Why isn't colchicine widely used clinically? Why isn't actinomycin widely used clinically? Why isn't chloramphenicol widely used clinically? Why isn't Cytoxan widely used clinically? Why isn't nitrogen mustard widely used clinically? Why isn't the use of drugs that inhibit nucleic acid synthesis widely used? [ Hide these questions ]

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