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When Burr failed to get the Republican nomination for the governorship of New York in 1804, he solicited Federalist aid, causing Hamilton to denounce Burr as "a man of irregular and insatiable ambition … who ought not to be trusted with the reins of the government." An agitated Burr challenged Hamilton to a duel, to which Hamilton agreed, although he issued a letter stating that compliance with the duel would prevent him from seeking further political involvement, an ironic publication since Hamilton was mortally wounded in the duel.
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